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1

Rational design of cationic lipids for siRNA delivery

Semple, Sean C, Akinc, Akin, Chen, Jianxin, Sandhu, Ammen P, Mui, Barbara L, Cho, Connie K, Sah, Dinah W Y, Stebbing, Derrick, Crosley, Erin J, Yaworski, Ed

Journal:

Nature Biotechnology

Année:

2010

Langue:

english

Fichier:

PDF, 408 KB

english, 2010

2

Bridging barriers to advance multisector approaches to improve food security, nutrition and population health in Nepal: transdisciplinary perspectives

Gaihre, Santosh, Kyle, Janet, Semple, Sean, Smith, Jo, Marais, Debbi, Subedi, Madhu, Morgan, Heather

Journal:

BMC Public Health

Année:

2019

Langue:

english

Fichier:

PDF, 956 KB

english, 2019

3

Covid-19: Protecting Worker Health

Semple, Sean, Cherrie, John W

Journal:

Annals of Work Exposures and Health

Année:

2020

Langue:

english

Fichier:

PDF, 165 KB

english, 2020

4

Comparative evaluation of cytokine profiles and reactive gliosis supports a critical role for interleukin-6 in neuron-glia signaling during regeneration

Wolfgang J. Streit, Sean D. Hurley, Tanya S. McGraw, Susan L. Semple-Rowland

Journal:

Journal of Neuroscience Research

Année:

2000

Langue:

english

Fichier:

PDF, 382 KB

english, 2000

5

Interactions of liposomes and lipid-based carrier systems with blood proteins: Relation to clearance behaviour in vivo

Sean C Semple, Arcadio Chonn, Pieter R Cullis

Journal:

Advanced Drug Delivery Reviews

Année:

1998

Langue:

english

Fichier:

PDF, 531 KB

english, 1998

6

Efficient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures

Sean C. Semple, Sandra K. Klimuk, Troy O. Harasym, Nancy Dos Santos, Steven M. Ansell, Kim F. Wong, Norbert Maurer, Holger Stark, Pieter R. Cullis, Michael J. Hope, Peter Scherrer

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

2001

Langue:

english

Fichier:

PDF, 940 KB

english, 2001

7

The relationship between workers’ self-reported changes in health and their attitudes towards a workplace intervention: lessons from smoke-free legislation across the UK hospitality industry

Laura MacCalman, Sean Semple, Karen S Galea, Martie Van Tongeren, Scott Dempsey, Shona Hilton, Ivan Gee, Jon G Ayres

Journal:

BMC Public Health

Année:

2012

Langue:

english

Fichier:

PDF, 226 KB

english, 2012

8

Classroom Carbon Dioxide Concentration, School Attendance, and Educational Attainment

Gaihre, Santosh, Semple, Sean, Miller, Janice, Fielding, Shona, Turner, Steve

Journal:

Journal of School Health

Année:

2014

Langue:

english

Fichier:

PDF, 509 KB

english, 2014

9

Personal exposure monitoring of PM2.5 in indoor and outdoor microenvironments

Steinle, Susanne, Reis, Stefan, Sabel, Clive E., Semple, Sean, Twigg, Marsailidh M., Braban, Christine F., Leeson, Sarah R., Heal, Mathew R., Harrison, David, Lin, Chun, Wu, Hao

Journal:

Science of The Total Environment

Année:

2015

Langue:

english

Fichier:

PDF, 2.00 MB

english, 2015

10

PHARMACOKINETICS AND TISSUE RESIDUES OF TELAZOL® IN FREE-RANGING POLAR BEARS

Semple, Hugh A., Gorecki, Dennis K. J., Farley, Sean D., Ramsay, Malcolm A.

Journal:

Journal of Wildlife Diseases

Année:

2000

Langue:

english

Fichier:

PDF, 110 KB

english, 2000

11

Effectiveness of interventions to reduce household air pollution and/or improve health in homes using solid fuel in low-and-middle income countries: A systematic review and meta-analysis

Quansah, Reginald, Semple, Sean, Ochieng, Caroline A., Juvekar, Sanjar, Armah, Frederick Ato, Luginaah, Isaac, Emina, Jacques

Journal:

Environment International

Année:

2017

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2017

12

Recommendations of the Oligonucleotide Safety Working Group's Formulated Oligonucleotide Subcommittee for the Safety Assessment of Formulated Oligonucleotide-Based Therapeutics

Marlowe, Jennifer L., Akopian, Violetta, Karmali, Priya, Kornbrust, Douglas, Lockridge, Jennifer, Semple, Sean

Journal:

Nucleic Acid Therapeutics (Formerly Oligonucleotides)

Année:

2017

Langue:

english

Fichier:

PDF, 275 KB

english, 2017

13

“How do you know those particles are from cigarettes?”: An algorithm to help differentiate second-hand tobacco smoke from background sources of household fine particulate matter

Dobson, Ruaraidh, Semple, Sean

Journal:

Environmental Research

Année:

2018

Langue:

english

Fichier:

PDF, 267 KB

english, 2018

14

Using air-quality feedback to encourage disadvantaged parents to create a smoke-free home: Results from a randomised controlled trial

Semple, Sean, Turner, Stephen, O'Donnell, Rachel, Adams, Lynn, Henderson, Tracy, Mitchell, Shirley, Lyttle, Susan, Amos, Amanda

Journal:

Environment International

Année:

2018

Langue:

english

Fichier:

PDF, 551 KB

english, 2018

15

Fathers’ Views and Experiences of Creating a Smoke-Free Home: A Scoping Review

O’Donnell, Rachel, Angus, Kathryn, McCulloch, Peter, Amos, Amanda, Greaves, Lorraine, Semple, Sean

Journal:

International Journal of Environmental Research and Public Health

Année:

2019

Langue:

english

Fichier:

PDF, 876 KB

english, 2019

16

Measuring Air Quality for Advocacy in Africa (MA3): Feasibility and Practicality of Longitudinal Ambient PM2.5 Measurement Using Low-Cost Sensors

Awokola, Babatunde I., Okello, Gabriel, Mortimer, Kevin J., Jewell, Christopher P., Erhart, Annette, Semple, Sean

Journal:

International Journal of Environmental Research and Public Health

Année:

2020

Fichier:

PDF, 902 KB

2020

17

Cytokine transcripts expressed by microglia in vitro are not expressed by ameboid microglia of the developing rat central nervous system

Sean D. Hurley, Sharon A. Walter, Susan L. Semple-Rowland, Wolfgang J. Streit

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 139 KB

english, 1999

18

In vivo administration of liposomal vincristine sensitizes drug-resistant human solid tumors

Carlo Leonetti, Marco Scarsella, Sean C. Semple, Agnese Molinari, Carmen D'Angelo, Antonella Stoppacciaro, Annamaria Biroccio, Gabriella Zupi

Journal:

International Journal of Cancer

Année:

2004

Langue:

english

Fichier:

PDF, 412 KB

english, 2004

19

Optimization and characterization of a sphingomyelin/cholesterol liposome formulation of vinorelbine with promising antitumor activity

Sean C. Semple, Robert Leone, Jinfang Wang, Esther C. Leng, Sandra K. Klimuk, Merete L. Eisenhardt, Zuan-Ning Yuan, Katarina Edwards, Norbert Maurer, Michael J. Hope, Pieter R. Cullis, Quet-Fah Ahkong

Journal:

Journal of Pharmaceutical Sciences

Année:

2005

Langue:

english

Fichier:

PDF, 233 KB

english, 2005

20

A survey of schoolchildren's exposure to secondhand smoke in Malaysia

Emilia Zainal Abidin, Sean Semple, Affandi Omar, Hejar A Rahman, Stephen W Turner, Jon G Ayres

Journal:

BMC Public Health

Année:

2011

Langue:

english

Fichier:

PDF, 320 KB

english, 2011

21

Therapeutic integration of c-myc and bcl-2 antisense molecules with docetaxel in a preclinical model of hormone-refractory prostate cancer

Carlo Leonetti, Annamaria Biroccio, Carmen D'Angelo, Sean. C. Semple, Marco Scarsella, Gabriella Zupi

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 344 KB

english, 2007

22

Encapsulation in liposomal nanoparticles enhances the immunostimulatory, adjuvant and anti-tumor activity of subcutaneously administered CpG ODN

Susan de Jong, Ghania Chikh, Laura Sekirov, Sam Raney, Sean Semple, Sandra Klimuk, Ning Yuan, Micheal Hope, Pieter Cullis, Ying Tam

Journal:

Cancer Immunology, Immunotherapy

Année:

2007

Langue:

english

Fichier:

PDF, 427 KB

english, 2007

23

The importance of reliable exposure estimates in deciding whether trichloroethylene can cause kidney cancer

John W. Cherrie, Hans Kromhout, Sean Semple

Journal:

Journal of Cancer Research and Clinical Oncology

Année:

2001

Langue:

english

Fichier:

PDF, 63 KB

english, 2001

24

Epicutaneous Application of CpG Oligodeoxynucleotides with Peptide or Protein Antigen Promotes the Generation of CTL

Klimuk, Sandra K., Najar, Hossain M., Semple, Sean C., Aslanian, Soudabeh, Dutz, Jan P.

Journal:

The Journal of Investigative Dermatology

Année:

2004

Langue:

english

Fichier:

PDF, 193 KB

english, 2004

25

Distribution of pacemaker function through the tunica muscularis of the canine gastric antrum

Kazuhide Horiguchi, Garreth S. A. Semple, Kenton M. Sanders, Sean M. Ward

Journal:

The Journal of Physiology

Année:

2001

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2001

26

Encapsulation of c-myc antisense oligodeoxynucleotides in lipid particles improves antitumoral efficacy in vivo in a human melanoma line

Leonetti, Carlo, Biroccio, Annamaria, Benassi, Barbara, Stringaro, Annarita, Stoppacciaro, Antonella, Semple, Sean C, Zupi, Gabriella

Journal:

Cancer Gene Therapy

Année:

2001

Langue:

english

Fichier:

PDF, 2.45 MB

english, 2001

27

Role of c-myc protein in hormone refractory prostate carcinoma: cellular response to paclitaxel

Giuliana Cassinelli, Rosanna Supino, Valentina Zuco, Cinzia Lanzi, A.Ivana Scovassi, Sean C Semple, Franco Zunino

Journal:

Biochemical Pharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 356 KB

english, 2004

28

Liposome-encapsulated vincristine, vinblastine and vinorelbine: A comparative study of drug loading and retention

Igor V. Zhigaltsev, Norbert Maurer, Quet-Fah Akhong, Robert Leone, Esther Leng, Jinfang Wang, Sean C. Semple, Pieter R. Cullis

Journal:

Journal of Controlled Release

Année:

2005

Langue:

english

Fichier:

PDF, 164 KB

english, 2005

29

Expectations and changing attitudes of bar workers before and after the implementation of smoke-free legislation in Scotland

Shona Hilton, Sean Semple, Brian G Miller, Laura MacCalman, Mark Petticrew, Scott Dempsey, Audrey Naji, Jon G Ayres

Journal:

BMC Public Health

Année:

2007

Langue:

english

Fichier:

PDF, 282 KB

english, 2007

30

Covert observation in practice: lessons from the evaluation of the prohibition of smoking in public places in Scotland

Mark Petticrew, Sean Semple, Shona Hilton, Kaen S Creely, Douglas Eadie, Deborah Ritchie, Catherine Ferrell, Yvette Christopher, Fintan Hurley

Journal:

BMC Public Health

Année:

2007

Langue:

english

Fichier:

PDF, 252 KB

english, 2007

31

What's new in … Diabetes treatment

Sean F Dinneen, Robert K Semple

Journal:

Medicine (Medicine Publishing Company Ltd)

Année:

2002

Langue:

english

Fichier:

PDF, 75 KB

english, 2002

32

Cytokine mRNA Profiles in Contused Spinal Cord and Axotomized Facial Nucleus Suggest a Beneficial Role for Inflammation and Gliosis

Wolfgang J. Streit, Susan L. Semple-Rowland, Sean D. Hurley, Rehae C. Miller, Phillip G. Popovich, Bradford T. Stokes

Journal:

Experimental Neurology

Année:

1998

Langue:

english

Fichier:

PDF, 2.57 MB

english, 1998

33

A 6.9-Mb High-Resolution BAC/PAC Contig of Human 4p15.3–p16.1, a Candidate Region for Bipolar Affective Disorder

Kathryn L. Evans, Stephanie Le Hellard, Stewart W. Morris, Diane Lawson, Claire Whitton, Colin A.M. Semple, Judith A. Fantes, Helen S. Torrance, M.Pat Malloy, John C. Maule, Sean J. Humphray, Mark T.

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 228 KB

english, 2001

34

Separation of large unilamellar liposomes from blood components by a spin column procedure: towards identifying plasma proteins which mediate liposome clearance in vivo

Arcadio Chonn, Sean C. Semple, Pieter R. Cullis

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

1991

Langue:

english

Fichier:

PDF, 1.36 MB

english, 1991

35

Influence of dose on liposome clearance: critical role of blood proteins

Conrad D. Oja, Sean C. Semple, Arcadio Chonn, Pieter R. Cullis

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

1996

Langue:

english

Fichier:

PDF, 716 KB

english, 1996

36

Therapeutically optimized rates of drug release can be achieved by varying the drug-to-lipid ratio in liposomal vincristine formulations

Michael J.W. Johnston, Sean C. Semple, Sandra K. Klimuk, Katarina Edwards, Merete L. Eisenhardt, Esther C. Leng, Göran Karlsson, Daniel Yanko, Pieter R. Cullis

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

2006

Langue:

english

Fichier:

PDF, 491 KB

english, 2006

37

Characterization of the drug retention and pharmacokinetic properties of liposomal nanoparticles containing dihydrosphingomyelin

Michael J.W. Johnston, Sean C. Semple, Sandy K. Klimuk, Steve Ansell, Norbert Maurer, Pieter R. Cullis

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

2007

Langue:

english

Fichier:

PDF, 295 KB

english, 2007

38

The ‘take home’ burden of workplace sensitizers: Flour contamination in bakers' families

Nara Tagiyeva, Siti Marwanis Anua, Sean Semple, Finlay Dick, Graham Devereux

Journal:

Environment International

Année:

2012

Langue:

english

Fichier:

PDF, 188 KB

english, 2012

39

Contact hypersensitivity: a simple model for the characterization of disease-site targeting by liposomes

Sandra K. Klimuk, Sean C. Semple, Peter Scherrer, Michael J. Hope

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

1999

Langue:

english

Fichier:

PDF, 288 KB

english, 1999

40

Spontaneous Entrapment of Polynucleotides upon Electrostatic Interaction with Ethanol-Destabilized Cationic Liposomes

Maurer, Norbert, Wong, Kim F., Stark, Holger, Louie, Lenore, McIntosh, Deirdre, Wong, Tabitha, Scherrer, Peter, Semple, Sean C., Cullis, Pieter R.

Journal:

Biophysical Journal

Année:

2001

Langue:

english

Fichier:

PDF, 1.57 MB

english, 2001

41

What's new in … Diabetes prevention and delivery of care

Sean F Dinneen, Robert K Semple

Journal:

Medicine (Medicine Publishing Company Ltd)

Année:

2002

Langue:

english

Fichier:

PDF, 83 KB

english, 2002

42

Application of Oligo-(14-amino-3,6,9,12-tetraoxatetradecanoic acid) Lipid Conjugates as Steric Barrier Molecules in Liposomal Formulations

Ansell, Steven M., Kojic, Ljiljana D., Hankins, Janet S., Sekirov, Laura, Boey, Anthony, Lee, Dora K., Bennett, Athena R., Klimuk, Sandra K., Harasym, Troy O., Santos, Nancy Dos, Semple, Sean C.

Journal:

Bioconjugate Chemistry

Année:

1999

Langue:

english

Fichier:

PDF, 247 KB

english, 1999

43

Monitoring for Health Hazards at Work (Cherrie/Monitoring for Health Hazards at Work) || Non-Ionising Radiation

Cherrie, John W., Howie, Robin M., Semple, Sean

Année:

2010

Langue:

english

Fichier:

PDF, 2.68 MB

english, 2010

44

[ACM Press the 51st ACM Southeast Conference - Savannah, Georgia (2013.04.04-2013.04.06)] Proceedings of the 51st ACM Southeast Conference on - ACMSE '13 - Applying static analysis to high-dimensional malicious application detection

Semple, Sean, Ponomarev, Stanislav, Durand, Jan, Atkison, Travis

Année:

2013

Langue:

english

Fichier:

PDF, 73 KB

english, 2013

45

Commentary: Switching to biogas – What effect could it have on indoor air quality and human health?

Semple, Sean, Apsley, Andrew, Wushishi, Adamu, Smith, Jo

Journal:

Biomass and Bioenergy

Année:

2014

Langue:

english

Fichier:

PDF, 430 KB

english, 2014

46

Children's Health 2010 || The Global Burden of Air Pollution on Mortality: The Need to Include Exposure to Household Biomass Fuel—Derived Particulates

Jamie Rylance, Duncan G. Fullerton, Sean Semple and Jon G. Ayres

Journal:

Environmental Health Perspectives

Année:

2010

Langue:

english

Fichier:

PDF, 284 KB

english, 2010

47

Airborne Endotoxin Concentrations in Homes Burning Biomass Fuel

Sean Semple, Delan Devakumar, Duncan G. Fullerton, Peter S. Thorne, Nervana Metwali, Anthony Costello, Stephen B. Gordon, Dharma S. Manandhar and Jon G. Ayres

Journal:

Environmental Health Perspectives

Année:

2010

Langue:

english

Fichier:

PDF, 1.14 MB

english, 2010

48

The relationship between air pollution and asthma in Malaysian schoolchildren

Zainal Abidin, Emilia, Semple, Sean, Rasdi, Irniza, Ismail, Sharifah Norkhadijah Syed, Ayres, Jon G.

Journal:

Air Quality, Atmosphere & Health

Année:

2014

Langue:

english

Fichier:

PDF, 530 KB

english, 2014

49

Influence of Cholesterol on the Association of Plasma Proteins with Liposomes †

Semple, Sean C., Chonn, Arcadio, Cullis, Pieter R.

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 218 KB

english, 1996

50

[Methods in Enzymology] Antisense Technology Part A: General Methods, Methods of Delivery, and RNA Studies Volume 313 || Lipid-based formulations of antisense oligonucleotides for systemic delivery applications

Semple, Sean C.

Année:

2000

Langue:

english

Fichier:

PDF, 2.11 MB

english, 2000